Dr. Edward Huttlin
Ed Huttlin is an Instructor in the Department of Cell Biology at Harvard Medical School, where he oversees the BioPlex project– a longstanding effort to profile protein-protein interactions in human cells via affinity-purification mass spectrometry (bioplex.hms.harvard.edu)– as co-Principal Investigator along with Professors Steve Gygi and Wade Harper. In this capacity, Ed is responsible for all aspects of quality control, data analysis, and dissemination.
Although his recent work is heavily computational, Ed earned his PhD in Biochemistry at the University of Wisconsin, Madison, working in the lab of Professor Michael Sussman on quantitative proteomics applications of in vivo 15N metabolic labeling in organisms ranging from Arabidopsis to mice. He then joined the lab of Steve Gygi at Harvard where he has participated in development of isobaric labeling technology and led an effort to profile protein expression and phosphorylation across nine mouse tissues prior to assuming responsibility for the BioPlex project.