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After closely monitoring the COVID 19 pandemic global risk assessment by the World Health Organization, on behalf of the HUPO Executive Committee, we wish to share with you that the HUPO 2021 annual congress, originally scheduled for October 24-28, 2021 in Stockholm, Sweden will take place as a virtual congress on November 15-19, 2021.While HUPO Connect 2020 was a great success as a virtual congress, the feedback we have received suggests we are all keen to meet in person again. The decision to postpone this year’s congress to November was made to increase the chance of having an in-person component to complement the virtual offering. So, building on the success of HUPO’s first virtual meeting ‘HUPO Connect 2020’, we are organizing HUPO ReCONNECT 2021. Whether fully virtual, we are aiming to provide the best HUPO congress ever. With an exciting scientific program, strong Early Career Researcher (ECR) involvement, and innovative virtual networking opportunities, you won’t want to miss HUPO ReCONNECT 2021! The most up to date information can be found here at www.hupo2021.org. In the meantime, please stay safe and healthy. Yu-Ju Chen HUPO President on behalf of the HUPO Executive Committee